This is the Record of Decision (ROD) for the Final Environmental Impact Statement for DOE Activities in Support of Commercial Production of High-Assay Low-Enriched Uranium (HALEU) (DOE/EIS-0559), signed December 20, 2024. DOE's Office of Nuclear Energy selects the Proposed Action: procuring up to 290 metric tons of HALEU enriched to at least 19.75 and less than 20 weight percent U-235 from commercial sources over a 10-year period, and facilitating establishment of a domestic commercial HALEU fuel cycle. The EIS evaluated two alternatives. Impacts are rated generally SMALL to MODERATE. No site-specific locations are selected in this ROD; future facility siting will require separate regulatory and NEPA review.12