The EPA Office of Pesticide Programs published a Notice of Availability on December 10, 2024, proposing that registration review is complete and no further review is necessary for four pesticides: alpha methyl mannoside, Duddingtonia flagrans strain IAH 1297, Pepino mosaic virus strain CH2 isolate 1906, and sheep fat. EPA finds all four present very low toxicity, exposure, and risk to human health and the environment, with no incidents reported since initial registration and no changes in use patterns or risk profiles. A 60-day public comment period runs through February 10, 2025. This is a procedural FIFRA section 3(g) registration review notice, not a NEPA environmental impact document.1